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494: How Exercise and Creatine Work Together to Fight Depression | Nicholas Fabiano, MD

The Genius Life

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Understanding Depression Through Exercise and BDNF

This chapter explores the complexities of depression, challenging the traditional serotonin hypothesis while emphasizing the crucial role of brain-derived neurotrophic factor (BDNF) and exercise. It highlights how physical activity not only boosts BDNF levels but also fosters social connections, enhancing mental well-being. Additionally, the chapter critiques the oversimplification of depression, advocating for more personalized treatment approaches that consider the multifaceted nature of mood disorders.

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