Episode 115: AML Series, Pt. 1 - CHIP, CCUS, ICUS, oh my!
The Fellow on Call: The Heme/Onc Podcast
Understanding Clonal Hematopoiesis and Variant Allele Frequencies
This chapter explores clonal hematopoiesis of indeterminate potential (CHIP), detailing the significance of identifying mutations linked to leukemia in patients without hematologic malignancies. It also addresses the complexities of interpreting next-generation sequencing results, particularly focusing on variant allele frequencies (VAF) and their implications for patient prognosis and treatment responses.
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