Innovating Dentistry with Digital Fabrication

Explore the frontiers of 3D printing in healthcare and its potential to revolutionize personalized medicine, reshape prosthetics, and reimagine drug delivery systems.

In this episode we're re-sharing a conversation Russ had in 2021 with Joseph DeSimone, a professor of chemical engineering at Stanford University. This one is about health, and Joe tells us how 3D printing is transforming healthcare. His group is using it to make vaccine delivery easier and more effective. They're also creating implantable chemotherapy that kills tumors, while having fewer side effects for the patients. 

We hope you enjoy this glimpse of how 3D printing technologies are being used in novel and unexpected ways.

Chapter show notes:

(00:00:00) Introduction

Host Russ Altman introduces the episode and welcomes Joseph DeSimone, a renowned 3D printing expert and bioengineer.

(00:01:14) Exploring the Potential of 3D Printing in Healthcare

Altman and DeSimone discuss the transformative possibilities of 3D printing in personalized medicine, prosthetics, and drug delivery.

(00:04:25) Advancements in Personalized Prosthetics

The advancements in 3D printing technology for personalized prosthetics are explored, highlighting the benefits of customized solutions for patients.

(00:07:36) Innovations in Implantable Devices

DeSimone discusses the groundbreaking use of 3D printing for creating implantable devices, such as bone replacements and joint implants, with improved functionality and longevity.

(00:09:19) Custom Prosthetics and Implants

The use of 3D printing for custom prosthetics and implants is highlighted, showcasing its potential for improving patient outcomes.

(00:11:05) Enhancing Drug Delivery through 3D Printing

DeSimone explains how 3D printing has revolutionized drug delivery systems, allowing for precise control and targeted release of medications to enhance therapeutic outcomes.

(00:13:10) Precision Drug Delivery for Cancer Treatment

DeSimone discusses the implantable devices used for targeted chemotherapy delivery, including a description of their appearance and components. 

(00:15:40) Applications of localized drug delivery in various cancers are explored.

(00:20:10) Advanced Materials for Bioprinting

The use of bioprinting and the development of advanced materials for creating functional tissues and organs are discussed, highlighting their potential impact on regenerative medicine.

(00:22:15) Harnessing 3D Printing for Regenerative Medicine

The potential of 3D printing in regenerative medicine, including tissue engineering and organ transplantation, is examined, highlighting its ability to create patient-specific solutions.

(00:23:35) Ensuring Data Security and Patient Privacy

The importance of data security and patient privacy in the context of 3D printing healthcare solutions is emphasized, exploring strategies to safeguard sensitive information.

(00:25:05) Trust and Ethics in 3D Printing Healthcare

The ethical considerations and challenges surrounding 3D printing in healthcare, including regulatory frameworks and patient privacy, are discussed.

(00:27:14) Diversity and Trust in Bioengineering and Healthcare

DeSimone discusses his involvement in issues of diversity and trust within bioengineering and healthcare. The connection between values, diversity, and fostering an innovative environment is examined.

(00:28:30) The Mathematical Impact of Diversity

Altman and DeSimone discuss the tangible benefits of diverse teams in driving progress and innovative solutions. The concept of combinatorial approaches and the need for diversity in disciplines and human experiences is highlighted.

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