The Effectiveness of Magnesium Supplementation for Nocturnal Leg Cramps

This chapter discusses the effectiveness of magnesium supplementation for reducing Nocturnal Leg Cramps. A systematic review of 11 RCTs found no evidence of benefit. However, there is limited evidence from a single randomized double-blind trial that oral magnesium oxide supplementation may improve Nocturnal Leg Cramps if patients use it for at least 60 days.