Ep 180 Acetaminophen Poisoning – Pitfalls in Assessment and Management
Emergency Medicine Cases
Acute Hepatic Failure and Acetaminophen Toxicity
Anton: acetaminophen toxicity, no matter who you are when untreated, the final outcome has the potential to be acute liver failure. The other pearl is that when you have a very high acetaminophen level on first presentation and your INR also goes up because there's an interference of acetaminophen with the InR assay. An elevated INR may be 1.4, which in six hours goes back down to 1.0, and then starts to rise as you get hepatic failure. Anton: I would add though that even patients who aren't showing those symptoms can trigger us to get more aggressive if we're not already worried about them.
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