Clinical psychologist and bestselling author Dr. Lisa Miller joins us to reveal the groundbreaking neuroscience that connects spirituality with mental health, purpose, and human flourishing. Drawing from decades of research at Columbia University, she shares how spiritual awareness literally changes the brain — rewiring us for resilience, compassion, and meaning. From the awakened brain to the power of awe, Lisa bridges empirical science with lived spirituality, showing how we are biologically built for connection with something greater than ourselves.

www.bioptimizers.com/knowthyself

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Andrés Book Recs: https://www.knowthyselfpodcast.com/book-list

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00:00 Intro03:40 What Is the Awakened Brain?07:10 How Spirituality Changes the Brain10:50 Depression as a Doorway to Awakening14:25 The Biology of Faith and Meaning18:05 The Parietal Lobe and the Sense of Oneness22:00 From Egoic Mind to Spiritual Awareness26:15 Dorsal vs. Ventral Attention Networks Explained30:10 How Prayer and Meditation Rewire the Brain34:00 The Neuroscience of Love and Connection38:25 What Happens in the Brain During Awe42:10 Synchronicity and the Science of Guidance46:00 Raising Spiritually Connected Children50:20 Addiction, Recovery, and the Search for Spirit54:35 The Brain as an Antenna for Consciousness59:15 Science Meets Mysticism: Where They Overlap1:03:30 The Future of Mental Health and Spirituality1:07:40 Reawakening the Innate Spiritual Brain1:12:00 Living with Awe, Service, and Gratitude1:16:10 Closing Reflections

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Episode Resources:

https://www.lisamillerphd.com/

https://www.instagram.com/dr.lisamiller/

https://www.instagram.com/andreduqum/

https://www.instagram.com/knowthyself/

https://www.youtube.com/@knowthyselfpodcast

https://www.knowthyselfpodcast.com

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