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TWiN 31: HIV-1 co-receptor shapes window for memory linking

This Week in Neuroscience

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Inhibition of CCR5 During Learning

In the first experiment, they exposed mice to context A and then shone a light into the hippocampus which would activate CCR5. But that activation did not impair just the actual association of the shock with context B. So this did not interfere with the actual learning of the original association. The degree of freezing in B is still equal to that of before without just the apply. And again, when they do that, they see less linking so that the mice don't freeze in context A even after five hour gap.

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