The Fellow on Call: The Heme/Onc Podcast cover image

Episode 042: Myeloma Series, Pt.3 - Intro to Multiple Myeloma

The Fellow on Call: The Heme/Onc Podcast

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Importance of Plasma Cell Percentage in Bone Marrow Biopsy

This chapter highlights the significance of accurately determining the plasma cell percentage in a bone marrow biopsy. It discusses the limitations of flow cytometry in estimating plasma cell percentage and recommends the use of immunohistochemistry on core biopsy for more accurate results. The chapter also touches on the patchy distribution of plasma cells and the usefulness of flow cytometry in identifying abnormal immunophenotype and tracking minimal residual disease.

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