TWiV 1133: Gain of function makes us safer
This Week in Virology
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Challenges with PCR Testing and Immune Response to Vaccines
The chapter covers challenges with PCR testing at the start of the pandemic, emphasizing the need to consider the infectivity timeline for positive individuals. It transitions into discussions about a more sensitive assay, cross-reactive epitopes between cold viruses and SARS-CoV-2, immune response to vaccines, and potential benefits of generating IgA and IgM antibodies for mucosal immunity. The conversation extends to Lassa fever research, spike proteins of arena viruses, and experiments involving human receptors in viral studies.
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