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Katalin Karikó — Forging the mRNA Revolution

The Joe Walker Podcast

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The Marriage of Immunology and mRNA

The body basically rejects the synthetic mRNA. It's immunogenic causes inflammation. So you're trying to work out how to basically mask the synthetic mRNA so that the cells accept it. And of course we found that most of the RNA did induce the immune response or RNA. Of course, in our body or RNA inside the cell. But when you have an injury, it comes out. You also get inflammatory reaction from that. We had no idea that we can, there is such such thing exists.

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