Is Purosemide a Venodilator?

If purosemide is increasing prostaglandin activity, it should be a venodilator. It should dilate arteries too. But the net effect on the arterial system appears to be null. And that is because of there is concomitant upregulation of the renin angiotessen aldosterone system as well at the same time which causes vasoconstriction through angiotensin.