The Benefits and Risks of Systemic Thrombolysis in Patients on DOACs

The November 2023 replay of past episodes showcases five interviews on topics in stroke. The episode begins with an interview with Dr. Imogene Scott on prehospital telestroke vs paramedic scores to accurately identify stroke reperfusion candidates. The episode continues with an interview with Dr. David Seiffge on the use of oral anticoagulants on ischemic stroke. The next interview is with Dr. Alejandro Rabinstein and Hassan Kobeissi on comparing outcomes between CTP and NCCT for endovascular therapy selection in the late therapeutic window. The fourth interview is with Dr. Thanh Nguyen discussing whether dual antiplatelet therapy is non-inferior to intravenous thrombolysis among patients with minor non-disabling acute ischemic stroke. The November Recall concludes with Dr. Seemant Chaturvedi discussing this year's European Stroke Organization Conference and pivotal trials that were presented during the conference.

Related Podcast Links:

Pre-Hospital Evaluation of Acute Stroke: EMS vs Telemed: https://directory.libsyn.com/episode/index/id/24928863

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants: https://directory.libsyn.com/episode/index/id/25736865 

CT Perfusion vs CT for Late Window Stroke Thrombectomy: https://directory.libsyn.com/episode/index/id/26673237

Dual Antiplatelet Therapy vs Alteplase for Patients With Acute Ischemic Stroke:  https://directory.libsyn.com/episode/index/id/27455412

Pivotal Stroke Trials Presented at this Year’s ESOC: https://directory.libsyn.com/episode/index/id/27279144

Related Article Links:

Prehospital Telestroke vs Paramedic Scores to Accurately Identify Stroke Reperfusion Candidates: A Cluster Randomized Controlled Trial: https://n.neurology.org/content/99/19/e2125

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants: https://jamanetwork.com/journals/jamaneurology/fullarticle/2799622

CT Perfusion vs Noncontrast CT for Late Window Stroke Thrombectomy: A Systematic Review and Meta-analysis: https://n.neurology.org/content/100/22/e2304

Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial: https://jamanetwork.com/journals/jama/article-abstract/2806532

ESOC Plenary: https://2023.eso-conference.org/programme/plenary-highlights/

Disclosures can be found at Neurology.org