3min chapter

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Dr. Robert Malenka: How Your Brain’s Reward Circuits Drive Your Choices

Huberman Lab

CHAPTER

The Role of the Serotonin 1B Receptor in the Neuroscience of MDMA

LZ Granderson: I completely agree about MDMA and we've done a couple of podcasts about psilocybin and by extension LSD. LZ: Even just differences in receptor subtypes leading to profoundly different subjective outcomes is one of the most important areas that one could even think about let alone work on. There are 16 different serotonin parking spots or receptors that are distributed in different brain areas in complex ways, but it also offers possibilities for developing very novel therapeutic agents That activate or inhibit these in complex ways,. hopefully for therapeutic benefit. lz: So I'm very excited about what's happening with the research on MDMA and I'm so glad that your laboratory has parsed some of the relative roles

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