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The Effect of Exercise on Bone Formation
The net effect of exercise over time on bone is going to be the synthesis of how these two opposing processes are being turned on. So I would think that if you're doing a weight supported exercise like cycling or swimming that may not turn on bone formation as effectively as a weight bearing exercise and you're getting this catabolic effect, that might be a condition where over time you could lose bone or at least not gain bone. But we have to entertain that just knowing that transient increases in PTH signaling induced by pharmacologics is very anabolic to bone. And then there's one more factor here. It's still possible that the increase in PTH is anabolic. You know, we