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CLL: MRD and first-in class agents

VJHemOnc Podcast

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Efficacy and Safety Results of Venetoclax versus Venetuzumab and Clorambacil in Chronic Lymphocytic Leukemia

This chapter presents the updated efficacy and safety results from the phase 3 CLL14 study comparing Venetoclax and Venetuzumab with Clorambacil in previously untreated patients with chronic lymphocytic leukemia. It discusses deep responses, minimal residual disease levels, next-line treatment, treatment-free duration, long-term toxicity, and secondary malignancies.

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