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#33 - Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin

The Peter Attia Drive

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Do You Want to Do a Dream Experiment?

There is a jean that was identified now ten, 12 years ago. Iwas identified by mark mc carthy and some other investigators in great britain as sending the strongest genetic signal for obesity,. or elevated body fat. There are various schools of thought about how this gen is doing it. What exactly is going on in the central nervous system is not clear. They have actually, in one study, pretty characteristic functional magnetic resonance imaging differences among individuals who do or don't have this variant. But the mechanism is unknown. And this is something which has intrigued me now for eight or ten years.

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