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The Fundamental Principles of Large Scale Drug Trials
In the past 25 years, clinical trials have become more and more complex. But why on 15 % of these drugs have gone through these clinical trials? Well, martin, having realized that treatments already in use often lacked a good evidence base, you decided to change things. The principles are quite simple really. What we're trying to do is work out whether, when we give a drug or we don't give a drug, which one's better. So that requires something called randamization. Let's think of it as a coin toss. And so actually use the coin toss essentially. If it comes down heads, i the people get aspirin. Now if it comes down tails, they