The Effects of Engraftment on the Microbiome

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Fecal transplants do an amazing job for recognizing the gut and eradicating that organism. We still don't exactly know what is in the mix of poo that is doing it. But there's no interventions currently that have been shown to modulate the microbiome in a way that would either improve their symptoms or potentially reverse the condition. People are looking at, okay, what if you intervene and get pre-treat with diet first? You kind of prime the gut with a supportive diet and then you give a fecal transplant or post transplant supportive diets.

Episode #267. Join me for a deep dive into the influence of the gut microbiome on inflammation and metabolic disease. In this fascinating exchange with Dr Suzanne Devkota, we explore the role of the gut in these conditions, shedding light on food allergies, IBD, and obesity. You’ll learn the practical tips you need to nurture a healthy microbiome, as well as gain a better understanding of what we do – and don’t – know about this incredible system.

Specifically, we discuss:

Intro (00:00)
The evolving field of microbiome research (02:13)
Gut microbe on social media (09:32)
Microbiome definition (12:48)
Why the focus on gut bacteria? (13:55)
Differences in Microbes (16:02)
Microbial shifts and adaptations (18:45)
Microbes perturbations (21:35)
Human microbiome in evolution (23:54)
Healthy microbiome and diversity (27:47)
Is the microbiome the sole driver of metabolic diseases? (33:05)
Dietary patterns and FODMAP intolerance (41:07)
Saturated fat and gut health (49:15)
Microbiome metabolites and heart disease risk (57:42)
Inflammatory bowel disease (IBD) and dysbiosis (1:02:09)
Food additives (1:12:29)
Supporting the microbiome in IBD (1:15:29)
Microbiome's interaction with fat cells (1:16:52)
Short-chain fatty acids and appetite regulation (1:29:26)
Practical tips for nourishing a healthy gut (1:31:05)
Microbiome's interaction with Polyphenols (1:38:43)
On supplements and fermented foods (1:39:15)
Factors affecting gut health beyond nutrition (1:46:22)
Outro (1:50:10)

Connect with Dr Suzanne Devkota on Instagram and Twitter. Learn more about her research at http://www.devkotalab.com/thelab.

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Enjoy, friends.

Simon

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Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

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