The number of evident syntheses concerning coverd 19 went through the roof as governments, local authorities and professional bodies flocked to commission them. This year, rader found 30 systematic reviews for convalescent plasma based on only 11 clinical trials. And none of the reviews had included all the trials. You have this huge amount of inappropriate and probably wasteful duplication of effort. One possible solution lies in prospero, a data base started in 20 11, in which researchers can register their planned systematic reviews.
A deluge of trials has stress-tested the systems that produce evidence.
Around the world, researchers have raced to test therapies to treat COVID-19. The speed and urgency of this task has revealed both the weaknesses in the collection and use of research-based evidence, and how well-run trials have helped save lives.
This is an audio version of our feature: How COVID broke the evidence pipeline
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