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Trial of the Week: DESIRE & In-Flight Medical Emergencies

Pharmacy to Dose: The Critical Care Podcast

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Evaluating Dexmedetomidine in Sepsis Management

This chapter reviews a JAMA-published clinical trial assessing dexmedetomidine's impact on mortality and ventilator-free days in mechanically ventilated sepsis patients across Japanese ICUs. It explores the trial's key findings and the implications of changing the primary outcome measure mid-study, advocating for more accurate patient outcomes in critical care settings.

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