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a16z Bio + Health #6: AI for Biologics With Mark DePristo and Peyton Greenside

a16z Live

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The Multi-Matrix Relationship in Drug Development

We're really fixated on questions of proxies for more downstream things you care about. So stability of the molecule is important, but in many cases, you actually care about things like refrigeration time. That kind of multimultidimensional relationship is something that we're learning on the fly and actively pursue data generation opportunities. We can basically build models that'll say things like, i know these types of mutations are stabilizing, but these specific subsets are also helpful for making sure that you survive three free thog cycles or allow you to be inhalable.

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