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Self Experiments In the Biochemically Unoptimized State

Mastering Nutrition

CHAPTER

The Effects of Protein on Lactate Levels

In 1977, a pyruvate carboxylase deficiency patient had very elevated fasting lactate at just under 8 millimoles per liter. An intravenous bolus of glucose caused lactate to go up even further, not fall. It seems more obvious to me that protein would suppress lactate than that glucose would. Even if glucose can generate some aspartate, it will generate even more flux to glycolysis. So I believe my biochemical reasoning is better support in the statement from the textbook.

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