Brain Ponderings podcast with Mark Mattson cover image

Pondering Cognitive Maps with Jim Knierim

Brain Ponderings podcast with Mark Mattson

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How Do Pattern Separation and Dente Gyrus Work?

As you get older, it's harder and harder for you to remember that you saw this and not this. The thought is that brain mechanisms that take these similar inputs make them more different from each other. In the visual cortex, they're represented by very similar neurons because they are very similar visually. That's what allows a young person to recognize that you've shown me this, not this. But conceptually, they can remember them differently because the hippocampus has made them very distinct.

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