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Episode 24. ASCO/EHA 2023 Special: Updates on CAR T-cell Therapy in Myeloma
Blood Cancer Talks
GPRC5D and BCMA Cartesal Therapy: A Comparison
GPRC5D CARs are active. There's actually been two Chinese trials that have been published with GPRC 5D CARs and showing very similar efficacy. So it does seem like you can rescue a patient even after a prior BCMA CAR with a GPRc5D CAR, which I thought was really nice to see now in multiple studies. Now, let's talk about safety. Any major differences in CRS or ICANN's rate between GPRC5d and BCMA Cartesal therapy that stood out to you? Not really. And compared to BCMA CARs, any differences in incidence of prolonged cytopenia beyond 30 or 60 days?
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