Episode 43 - When your number’s not up | Platelet Refractoriness
Bloody Minded
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Platelet Refractoriness and Immune Interactions
This chapter explores the complex relationship between platelets and the immune system, emphasizing how specific antigens on platelet surfaces can trigger immune responses. It discusses the implications of HLA compatibility in platelet transfusions, the mechanisms behind platelet refractoriness, and various testing methods for identifying antibodies. Additionally, it highlights innovative strategies for improving transfusion outcomes in patients with HLA antibodies.
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