Single Cell Atlases and Liver Regeneration After Acute Damage

We're going to talk about something we've been talking a lot about recently on the show, which is these single cell atlases. We know that the liver has this remarkable ability to regenerate. And even after acute damage, like in this particular situation, they were talking about acetaminophen acute acetaminophen or APAP intoxication. The surviving cells are upregulating these ancestral, these primordial immature gene pathways to reprogram to a peri-central state.