The Proth-Rambin and Factor 5 Mutations

There's the, is it fair to call them gain of function? I feel like nowadays that is a whole different connotation. The Proth-Rambin and the Factor 5 are the gain of function ones. And then there's the anti-thrombin, the protein C and protein S. Anything else that is your standard test? No, and that's an excellent question. It depends on who you talk to about how you should do this, right?