Brain Ponderings podcast with Mark Mattson cover image

Bioelectronic Medicine, the Vagus, and the Inflammatory Reflex with Kevin Tracey

Brain Ponderings podcast with Mark Mattson

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The C Elegans Vegas Nerve Reflexes Control Inflammation

C elegans is a primitive worm. It doesn't really have a Vegas nerve it only has a few nerves actually. But, but there's a colon there's a set of colonergic neurons and C elegans that is activated by the presence of pathogens. So here you have an evolutionarily ancient roundworm, arguably one of the most ancient animals that we study today that has us essentially an intact inflammatory reflex. And so we've, we've, because science reduction is, you know, our modern scientific world that you and I grew up in and live in today is a world of reduction is science. We have to keep reducing it to,. to the next first simplest first principle and prove

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