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#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
The Next Generation of Microfluidics
Next generation is forget the microfluidics altogether. Just use big bottles. How can you possibly do that with big bottles? So here's the idea. You dissociate all of your cells or all of your nuclei from complex cells like brain cells, which are very long and sticky so you can't do that. But if you have blood cells or if you have neuronal nuclei or brain nuclei, you can basically dissociate, let's say, a million cells. And now want to add a unique barcode in each one of a million cells using only big bottles. A hundred times a hundred times a 100 is a million unique barcodes in every single one of these cells
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