The Effects of Topical NR on Skin Elasticity

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I'm associated with another company now in Korea called Juvenis. It's basically a skin cream and a serum, both of which have 2% NR in them. And I've just gotten back from Korea, where we've obtained some human data on topical NR. So it's not only is it absorbed, but the data show there's about a 25% improvement in skin elasticity over eight weeks in participants.

Episode #272. In the quest for an extended lifespan, has science been led astray? Join me as I sit down with Professor Charles Brenner, a leading global expert in NAD biology, to examine the longevity field's claims and controversies.

From debunking common beliefs to questioning high-profile opinions, Dr Brenner delivers a refreshingly candid perspective on the science of aging. Tune in to explore why he believes there's no “cure” for aging, the limitations of animal studies, and what the future might hold for this complex field.

Specifically, we discuss:

Intro (00:00)
Do we have the genes to live beyond 120 years? (3:54)
The genetics of extreme longevity (14:18)
Longevity in the animal kingdom (18:26)
Why do we age, and the realities of extending lifespan (31:22)
How long can we live? (39:01)
NAD coenzymes and DNA repair (43:49)
"Anti-ageing" products (55:17)
Conflicts of interest and the integrity of scientific claims (1:01:08)
Discovering nicotinamide riboside (NR) (vitamin B3) (1:03:19)
Sirtuins as anti-ageing genes (1:09:22)
A rebuttal to Drs. David Sinclair and Lenny Guarente (1:19:13)
Seeking consensus on the study of human longevity (1:32:57)
The information theory of aging (1:43:19)
Dr. Charles Brenner's theory of ageing (2:00:28)
How to age better (2:03:30)
Dr. Brenner on the quality of life (2:09:05)
NR supplementation (2:10:09)
Moving beyond Yamanaka factors (2:15:02)
Outro (2:18:45)

Connect with Dr Charles Brenner on Twitter, and visit his website, https://www.brennerlab.net/, for more.

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Enjoy, friends.

Simon

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Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

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