In those days, there were no formal procedures around clinical trials. Drugs of just migrated out of the drug companies laboratories. The most famous example occur at the beginning of the nineties when sarahtonin was alleged to be the thing that caused depression. You didn't have enough happy sanatoning in your brain, that's why. Well, it turns out that scientific nonsense. And indeed, some of them affect sSarahtonin and increase it. Some of them decrease it. They both work equally well or equally badly.

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