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The Science of MDMA & Its Therapeutic Uses: Benefits & Risks
Huberman Lab
The Role of the Body in PTSD
PTSD is caused by the exact sorts of brain network activations that we were discussing earlier. Things like heightened levels of activation in the amygdala to insula pathway, which of course would exacerbate bodily sensations related to the trauma. Now, therefore, it should come as no surprise that if MDMA can reduce the levels of activity in the hippocampal to amygdala toinsula circuitry and can do so both while someone is under the effects of MDMA but then lead to persistent long lasting reductions in those brain networks,. Well, then it stands to reason that MDMA could be a valid therapeutic for the treatment of PTSD. There are about three to five studies in this area now that stand as large scale clinical trials
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