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Tales from an Italian crypt, and the science behind ‘dad bods’

Science Magazine Podcast

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Understanding Adipocyte Behavior in Aging

This chapter examines how fat tissue expands with age, focusing on the behavior of adipocyte precursor cells and their rapid increase in fat cell production. Researchers employ lineage tracing and single-cell sequencing techniques to identify specific cell populations, particularly committed pre-adipocytes in middle-aged mice, and their role in age-related fat accumulation. The findings challenge traditional views of fat gain, suggesting that these cellular changes may have complex implications for metabolic health.

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