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April 2023 Neurology Recall: Topics in Headache Series

Neurology® Podcast

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The Role of CDRP in Vasoconstriction

When we induced vasoconstriction of a cerebral vessel, the sensory fibers in the brain released CDRP to normalize the vasotone. I tried to translate that into vasospastin. If I applied blood on a cerebral vessel in vivo, we did that in cat experiments and CDRP could so tonormalize the tone. So that was, you can say, some kind of an anti-vacochonstrictor substance.

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