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Jun 23 2023 This Week in Cardiology

This Week in Cardiology

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The Traverse Study of Testosterone in Older Men

The New England Journal of Medicine published the Traverse Study, a non inferiority placebo controlled RCT of testosterone in older men who had preexisting or high risk of heart disease. There was no significant difference in prostate cancer and only very minor changes in systolic blood pressure. However, there were 14 more VTE events, that's 46% more. The trial required an upper bound of less than 1.5 for the hazard ratio of the primary endpoint.

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