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But Always See First with Dr. Roderick MacKinnon

Brain Matters

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The Importance of Selectivity in Oxygen Caging

Sodium can either be in water or in the binding site, but the binding site's actually too big for sodium. Potassium on the other hand, the protein has made a binding site that is just the size for potassium. So it's kind of an energetic wash and going from the water to the binding site. The solvation is essentially as good. We could spend so long, I would love to talk about just some of the things that came from there,. But due to kind of our time constraints, I'd love to maybe go to now.

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