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#82 – ID Literature Year in Review (LIVE from MAD-ID)
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Jepotidicin for Uncomplicated Urinary Tract Infection
Jepotidicin is a novel first in class oral antibiotic. It does inhibit DNA dry race and topo rice on race four. But notably, vancomyper sensitivity but protect against AKI. And this is a space we sorely need a drug, right? In the beautiful 2019 AMR reports that came out before COVID, we had made tremendous gains removing some of these resistant organisms. We saw KPC going down, Astaneda going down to Pseudomonas aeruginosus. I think what went up was community acquired infections like ESBLs which are associated with non-drugresistant E. coli. The biggest risk factors for having a multi-drug
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