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S 484: Women's Health Spotlight: How Much PMS is Normal? Examining Luteal Phase Cycle Symptoms and More!

Sam Miller Science

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The Relationship Between Estradiol and Progesterone

Estradiol and progesterone balance each other out in terms of water attention and puffiness as well. A common contributor to higher estrogen and lower progesterone profile is deficiency or suboptimal levels of vitamin B6. There's clearly a third component besides hormonal imbalances that could also be contributory here, particularly with PMDD.

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