The Importance of Reverse Cholesterol Transport

And so chances are you caught some of those people when they were just randomly higher than their own mean value. Therefore the overwhelming probabilities of those people are going to be closer to their mean value later. So one of the things I would want to look at is did the placebo group and the pomegranate group have a similar or different baseline value and the placebo group here had 1.52 millimeters for a baseline value, which is very similar to what they show in the graph and never state for the pomegranate group. Is that right? One? Yeah, that's right. So it's just over 1.5 here. So it, it, excuse me, it doesn't look like there's a regression of the mean effect. It looks like this is a real effect. But the fact that their presentation of this data is so terrible makes me, you know, not want to jump on the findings of this, of this study. It's, it's just a, it's a little sketchy. It's, and it's inappropriate. And I just, you know, I have to be caught up with wondering why did they not want to show us the placebo group's data here. My guess is that the placebo group's data was really noisy and that the differences were not statistically significant at any time point. And that it, that it went up and down in a way that did, made it a messy story rather than a clean story. And the, so the fact that they were, I'm reading into it, right? But the, in my mind, the fact that they had to remove the placebo group to show a clean story that had a graph that they liked means that this graph is misleadingly clean, right? So, you know, overall, my opinion is, is basically, is basically go back to the original principle. All you have to do to reverse atherosclerosis is remove the causes of atherosclerosis. So I don't think being caught up in narrow mechanisms of reverse cholesterol transport is, is the right way to think about it. And, you know, partly, part of this is I'm biased towards root cause thinking, right? And so I look at the process that we showed before and I say, what's going wrong here?

Can plant foods and their phytochemicals be used to reduce arterial plaque? | Masterjohn Q&A Files #315

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