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E160 - (CME) Novel Agents for Treating Major Depressive Disorder (MDD)

NEI Podcast

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The New Paradigm of Intermittent Treatment

Zeranolone is an oral version of alopregnanolone, the drug that's been approved for postpartum depression. And if you only have to take it for a two week course, you're not going to necessarily have some of the long term side effects that we see with our medicines like weight gain and sexual dysfunction. So that would be interesting. This medication, by the way, they're going to be submitting to the FDA. They also had a study called the choral study, where zeranolone was given in combination with the initiation of a traditional antidepressant and versus the antidepressant alone. And they found that the response was much faster. That's another way

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