The Immune System's Double-Edged Sword

This chapter examines the intricate relationship between stress, immune responses, and the reactivation of the Epstein-Barr Virus (EBV), particularly in relation to autoimmune diseases like lupus. It discusses how EBV reactivation leads to a decrease in invariant chain levels, affecting antigen presentation and potentially triggering autoimmune responses. Additionally, the chapter explores the evolutionary implications of these mechanisms and the dual role of the immune system in both protection and misregulation.