The Influence of TH3-Plus Mothers on Fetal Iron Homeostasis

Investigators say their experiments also revealed unexpected pathophysiological outcomes that could have implications for thalassemic pregnancy in humans. Notable outcomes included alterations in intestinal iron absorption and tissue distribution when comparing WT and TH3-plus dams. Authors: The impaired fetal growth may be explained by hypoxia and iron-related oxidative stress, or enhanced placental urethral poises.