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DDW Highlights: 6 November 2023
The Drug Discovery World Podcast
Efficient brain delivery of IDS enzyme using Apo-E2 tagged sequence
This chapter discusses the insertion of a newly developed IDS gene with an Apo-E2 tagged sequence, which facilitates efficient delivery of the enzyme to the brain. It explores the potential benefits of this approach in normalizing brain pathology and improving the condition of mice with hunter syndrome in preclinical studies.
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