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# Epi 57 - ICU Primary - Bedside Preparation - Albumin, PRBC and Blood Grouping

ICU Primary PrepCast

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What Is Cross Match?

Cross match is testing the donor blood compatibility with recipients serum and the donor to avoid serious serious transfusion reactions. A group and hold is just checking the patients blood for their blood group which is their aBO group and their recess blood type. The steps are something called the major cross match where any the aim is to bind any IgG antibodies from the recipient serum if present to their antigens on the red cell membrane of donors. And then you can wash all the serum at which washes out any unbound IgG in the serum. If there's no agglutination or a negative Coombs test, this whole mixture is then added with control cells which are known to have Ig

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