Is There a Connection Between Pregnancy and Lidocaine?

There is some data out there though I don't think it's very definitive at all about the potential connection of Tylenol use in pregnant women. It can lead to decreased alpha-1 acid glycoprotein levels which results in a higher concentration of free lidocaine. Local aesthetics we can talk about that just for a moment here. So obviously pregnant patients are going to be more sensitive the effects of local aesthetics like we talked about before in the internal physiology lecture. All right great and as far as I know no no issues with TylenOL is that right? No no issues at all of Tylanol not for the fetus at least.