The Safety of Early Versus Deferred ART for AIDS Patients

No significant differences were found between immediate and deferred arms in all examined endpoints, including clinical worsening and OI-associated complications. This finding is congruent with the results of the A5-164 study, a 2009 randomized strategy trial that previously explored the question of early versus deferred ART. The authors note that its risk is likely to vary by opportunistic infection such as cryptococal meningitis and tuberculosis.