I am not aware of any long term calorie restriction study in humans. You can do observational studies but it's pretty confounded. The theory about it is that it reduces inflammation or something like that because you're just about metabolism. So there is this notion that this way a lot of people have gotten into fasting. Emptor signaling happens to and you want that to go on and off.
We are on the cusp of a major transformation in healthcare. Using information gleaned from our blood and genes and tapping into the data revolution made possible by AI, doctors can catch the onset of disease years before symptoms arise, revolutionizing prevention. At top hospitals and a few innovative health-tech startups, scientists are working closely with patients to dramatically extend their “healthspan”―the number of healthy years before disease sets in. In The Age of Scientific Wellness, two visionary leaders of this revolution in health take us on a thrilling journey to this new frontier of medicine.
Hood, Price, and Shermer discuss: why we age and die • sickcare vs. healthcare • the 10 most popular drugs in the U.S. work for only about 10% of treated people • chronological age ≠ biological age • life expectancy, life span, longevity, and healthspan • why eliminating all cancers would only increase average life span by 3 years • genome vs. phenome • gut biome • optimizing brain function • brain plasticity • sleep, nutrition, exercise • Alzheimer’s • AI and quantum computing for better health.