The Complexity of Neuroanatomy

Neuroscientist Jessica Osterhout talks about the neural circuits of sickness behavior in fever and fever generation. It used to be thought that prostaglandin-sensiting led to thermoregulatory neurons driving things. That's why things like Tylenol and ibuprofen and aspirin reduce fever. But she was able to trace some of this to specific neurons, then use drug-inducible mice for septor-induced mice. So there's a lot of implications for therapy, especially if patients don't respond to Cylenol or... Probably ib uprofen.