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E160 - (CME) Novel Agents for Treating Major Depressive Disorder (MDD)

NEI Podcast

CHAPTER

The Effects of Psychedelics on Depression

There is evidence indicating exactly what you said. You will also increase dopamine tone in the motivation reward system as we talked about. As a correlate, there is increased glutamatergic transmission. And interestingly, we spoke about networks. There is increased connectedness in functional networks as a result of use of psychedelic agents. Yeah. I would imagine that could lead to improved cognition as well, which is... Possibly so. We need better studies to determine that, especially on glutenol studies, but it is clearly a possible implication.

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