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E160 - (CME) Novel Agents for Treating Major Depressive Disorder (MDD)

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The Effects of Psychedelics on Depression

There is evidence indicating exactly what you said. You will also increase dopamine tone in the motivation reward system as we talked about. As a correlate, there is increased glutamatergic transmission. And interestingly, we spoke about networks. There is increased connectedness in functional networks as a result of use of psychedelic agents. Yeah. I would imagine that could lead to improved cognition as well, which is... Possibly so. We need better studies to determine that, especially on glutenol studies, but it is clearly a possible implication.

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