The Toxicity of Local Anesthesia

Local anesthetic can do CNS toxicity are feelings of lightheadedness dizziness and then that's usually followed by visual and auditory disturbances people can have tinnitus difficulty focusing. The primary cardiac electrophysiologic effects of local anesthetics you'll see a decrease in the rate of depolarization in those fast conducting tissues of the perkinje fibers and ventricular muscle so some bradycardia. Extremely high concentrations for localAnesthesia will depress spontaneous pacemaker activity in the sinus node and result in sinus arrest based on animal studies. If a patient has profound cardiovascular depression or collapse after the administration of bupivicane rop Civicane then along it could be